Launch of the Dubai Women's Health Study Protocol in Frontiers

The recent publication in Frontiers in Global Women's Health marks a pivotal moment for women's health research in the United Arab Emirates. Titled 'Building a foundation to promote Women’s health research in Dubai: Study protocol for a project to investigate the feasibility of establishing a dedicated Women’s health biobank,' the article outlines the Dubai Women's Health Study. Led by researchers from Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU) and Dubai Health, this prospective cohort study aims to lay the groundwork for a specialized biobank focused on key women's health conditions prevalent in Dubai.

This initiative addresses longstanding gaps in region-specific data, particularly for diverse populations in this multicultural hub. With recruitment underway since July 2025 at Latifa Hospital, the study targets women diagnosed with polycystic ovary syndrome (PCOS, a hormonal disorder characterized by irregular periods, excess androgen levels, and polycystic ovaries), endometriosis (a condition where tissue similar to the uterine lining grows outside the uterus, causing pain and infertility), pre-eclampsia (a pregnancy complication involving high blood pressure and potential organ damage), and endometrial cancer (malignancy of the uterine lining). By collecting clinical data and biospecimens, the project evaluates feasibility metrics like recruitment rates and logistical viability, paving the way for translational research.

MBRU's involvement underscores its commitment to precision medicine and public health innovation, aligning with UAE's academic health system model where universities integrate education, research, and clinical care.

Background: Women's Health Challenges in the UAE Context

In the UAE, women's health intersects with the nation's 'Big 4' public health priorities: cardiovascular disease, injuries, cancers, and respiratory conditions. Conditions like PCOS elevate risks for cardiovascular issues and endometrial cancer, while pre-eclampsia heightens long-term heart disease susceptibility post-pregnancy. Endometriosis links to potential breast and endometrial cancer risks. The UAE's 2024 National Policy for Improving Women’s Health sets ambitious targets, such as reducing female cancer mortality from 70.3 to 23.24 per 100,000 and all-cause mortality to 62.77 per 100,000, emphasizing biobanks and bio-registries for data-driven solutions.

Dubai, home to over 200 nationalities, demands ethnically diverse research to capture unique genetic, environmental, and lifestyle factors. Globally, biobanks like the UK's Biobank or the US Women's Health Initiative have revolutionized insights but often lack Middle Eastern representation. Regionally, efforts like Qatar Biobank exist but are general population-focused, not women-specific. This study fills that void, supporting UN Sustainable Development Goals 3 (Good Health and Well-Being) and 5 (Gender Equality).

For aspiring researchers, opportunities abound in UAE higher education. Check out research jobs in UAE universities to contribute to such initiatives.

MBRU's Pivotal Role in UAE Higher Education Research

Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai's flagship graduate-level medical university, spearheads this effort through its College of Medicine and Research and Graduate Studies. Authors including William Atiomo, Fadi Mirza, Tom Loney, and others hold dual affiliations with MBRU and Dubai Health, exemplifying integrated academic-clinical partnerships.

MBRU's Dubai Health Biobank, with capacity for 7 million samples stored at -80°C using advanced Azenta BioStore technology, provides the infrastructure backbone. Funded by the Dubai Health Collaborative Stimulus Research Grant (CSRG-24-10) and Al Jalila Foundation, the project exemplifies how UAE universities drive national health agendas.

Students and faculty at MBRU benefit from hands-on involvement in protocol development—from grant award in October 2024 to Institutional Review Board (IRB) approval in February 2025. This model inspires similar collaborations across UAE colleges. Explore UAE higher ed opportunities or academic career advice to join.

Study Objectives and Innovative Design

The Dubai Women's Health Study employs a prospective cohort design, tracking participants forward in time to assess outcomes. Primary objectives split into biobank operations and condition-specific research:

• Build data infrastructure linking electronic health records (Epic EHR) via OpenSpecimen to biospecimens.
• Measure recruitment rates (target: 100 per condition for PCOS/endometriosis/pre-eclampsia, 30 for endometrial cancer; matched controls).
• Evaluate willingness to participate (aiming 50% rate), logistics (sample transport/storage), financial sustainability, and ethics compliance.
• Collect samples for initial studies: endometrial cancer risk in PCOS/endometriosis, Co-enzyme A in pre-eclampsia, genetic profiling of inherited endometrial cancers.

Reported per CONSORT for pilots and STROBE for cohorts, the 12-month recruitment (April 2025–April 2026) ensures rigorous standards.

Targeting Key Women's Health Conditions

• PCOS: Affects 5-20% globally; in UAE, linked to metabolic syndrome amid lifestyle shifts.
• Endometriosis: Impacts quality of life; harmonized with EPHect project questionnaires.
• Pre-eclampsia: Critical in pregnancy; stool/blood for metabolic insights.
• Endometrial Cancer: Rising with obesity/diabetes trends.

Read the full protocol for diagnostic criteria details (e.g., Rotterdam for PCOS).

Recruitment, Data Collection, and Ethics

At Latifa Women’s Hospital (Dubai Health's largest women's facility), clinicians identify eligibles (women ≥18, Dubai residents, diagnosed conditions). Trained assistants provide multilingual info sheets, obtain broad consents for future use. Samples: blood (PBMCs/serum/plasma), tissue (snap-frozen), stool (-80°C in RNAlater). Workflow: collection during routine care, processing per ISBER standards, anonymized storage.

Ethics: MBRU IRB-approved (MBRU IRB-2024-692), Helsinki-compliant, GDPR-aligned. Patient focus groups refined materials, capturing barriers/motivations.

Biobanking Excellence and Technological Integration

Dubai Health Biobank's automation and Epic integration enable longitudinal tracking. Future expansions: more conditions, private hospitals, perinatal mental health via DASS-21.

For researchers, this highlights UAE's biobanking prowess. Learn more via research assistant jobs.

Alignment with UAE National Health Policies

Supports UAE Vision 2031 and 2024 Women's Health Policy, fostering precision medicine. Potential for global collaborations, biomarker discovery, epidemiology.

MBRU's site showcases such impacts.

Future Outlook and Research Opportunities

Post-feasibility, longitudinal follow-up, genomics. Impacts: policy, treatments, equity. For academics, UAE higher ed booms—faculty positions await.

Photo by Saher Suthriwala on Unsplash

Career Insights and Calls to Action

This study exemplifies UAE higher ed's role. Rate professors at Rate My Professor, find higher ed jobs, or seek career advice. Engage via comments below.