Andrew McGuire is an Associate Professor in the Immunology and Vaccine Development Program within the Vaccine and Infectious Disease Division at Fred Hutchinson Cancer Center. He also serves as a member of the Pathogen-Associated Malignancies Integrated Research Center. Dr. McGuire earned a BSc in Molecular Biology and Genetics from the University of Guelph in 2004 and a PhD in Molecular and Cellular Biology from the same institution in 2011. As a molecular and cellular biologist, his research focuses on the design of HIV vaccines, specifically developing immunogens to elicit broadly neutralizing antibodies capable of protecting against diverse strains of the rapidly mutating virus. His laboratory additionally investigates the antibody response to natural infection with viral pathogens of public health importance, including Epstein-Barr virus, Kaposi sarcoma-associated herpesvirus, respiratory syncytial virus, and HIV-1, seeking to inform the design and testing of safe and effective vaccines against these agents. Current projects include the development, production, and assessment of novel immunogens to elicit broadly neutralizing antibodies against HIV-1 and the development and testing of vaccines against Epstein-Barr virus.
Dr. McGuire's work emphasizes structural and antibody studies with the ultimate aim of advancing vaccine development. He maintains an active research program at Fred Hutchinson Cancer Center dedicated to these areas of immunology and infectious disease prevention.