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National University of Singapore (NUS)

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About Julius

Julius Fredens is an Assistant Professor in the Department of Biochemistry at the Yong Loo Lin School of Medicine, National University of Singapore (NUS). He holds a Presidential Young Professorship and serves as Principal Investigator of the Synthetic Biology Translational Research Programme at NUS. He is also an Associate Investigator at the National Centre for Engineering Biology (NCEB) and holds an NRF Fellowship.

Fredens received his PhD from the University of Southern Denmark, where he developed SILAC for quantitative proteomics in C. elegans under the supervision of Nils Færgeman. He then conducted postdoctoral research with Jason Chin at the MRC Laboratory of Molecular Biology in Cambridge. During this time, he co-authored work on the first synthetic E. coli genome with a compressed genetic code and demonstrated its genetic resistance to bacteriophage. Fredens started his research group at NUS in 2021. His research specializations include synthetic biology and synthetic genomics, with a focus on method development and applications in genome engineering. His work has addressed topics such as engineering bacteria for improved growth on plastic-derived compounds and synthetic CO2-fixing metabolic pathways.

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