Rate My Professor Mirian Krystel

Mirian Krystel De Siqueira is a Postdoctoral Scholar in the Department of Genetics at Stanford University, where she works in the Barna Lab. She earned her Ph.D. in Molecular, Cellular and Integrative Physiology from the University of California, Los Angeles. Her research centers on adipocyte biology, with a focus on the translation machinery in adipose progenitors and its role in metabolism and obesity. A key publication is the 2024 paper titled PPARgamma-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity, published in Cell Reports, which examines how PPARgamma agonists influence ribosomal factors and translational selectivity in adipose tissue under obese conditions. Additional work includes a 2025 protocol for polysome profiling in primary differentiating murine adipocytes, published in STAR Protocols, and contributions to studies on adipose-tissue plasticity and interorgan metabolic signaling.

De Siqueira has received the American Heart Association Postdoctoral Fellowship in recognition of her research on ribosome-mediated control of lipid metabolism. Her publications also encompass earlier studies on microbiota configuration in immune optimization and infection-elicited metabolic adaptations, appearing in Proceedings of the National Academy of Sciences. These contributions highlight mechanisms linking cellular translation, adipose tissue function, and metabolic health. She maintains an active research profile through collaborations in the Barna Lab at Stanford.