MIT Rett Syndrome Study: Leaky Brain Vessels Genetic Cause | AcademicJobs
MIT researchers at Picower Institute identify how MECP2 mutations cause leaky brain blood vessels in Rett syndrome via miR-126-3p overexpression, paving way for new therapies.
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Professor Roger D. Kamm is the Cecil H. Green Distinguished Professor of Biological and Mechanical Engineering at the Massachusetts Institute of Technology. He earned a degree in Mechanical Engineering from Northwestern University. He subsequently received both a Master’s degree and a PhD in Mechanical Engineering from MIT. Since 1978, Professor Kamm has been a professor of Mechanical Engineering at MIT. He was one of the founding members of the Biological Engineering Department when it was created in 1998 and also holds an appointment as Professor of Biological Engineering.
Professor Kamm directs the Mechanobiology Lab. His research elucidates the fundamental nature of how cells sense and respond to mechanical stimuli and employs these principles to understand cell population behaviors such as the emergence of form and function. The work seeks new treatments for neurological diseases and cancer and develops tissue constructs for drug and toxicity screening. Both experimental and computational approaches are used. The Kamm research group focuses on five broad areas: Biological Machines/Microfluidics, Angiogenesis/Vasculogenesis, Neurological Diseases, Cancer, and Simulation and modeling. Professor Kamm has received numerous honors including election to the National Academy of Engineering and the Institute of Medicine.
MIT researchers at Picower Institute identify how MECP2 mutations cause leaky brain blood vessels in Rett syndrome via miR-126-3p overexpression, paving way for new therapies.