p53 Mutation Lung Cancer: VCU Achilles' Heel | AcademicJobs
VCU Massey researchers uncover a key weakness in p53 mutations driving lung cancer, paving the way for targeted therapies via checkpoint inhibitors.
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Swati Palit Deb is an Associate Professor in the Department of Biochemistry and Molecular Biology at the Virginia Commonwealth University School of Medicine. She is also affiliated with the Department of Microbiology and Immunology and the VCU Massey Cancer Center. Her primary research focuses on the mechanisms by which the p53 tumor suppressor protein and its negative regulator MDM2 control cell proliferation and survival in normal and cancer cells, with particular emphasis on lung cancer and related molecular pathways.
Dr. Deb earned her B.Sc. in Chemistry and M.Sc. in Biochemistry from Calcutta University and holds a Ph.D. She has been at Virginia Commonwealth University since 2000. She has authored or co-authored numerous publications, with over 2,900 citations across 82 works according to academic databases. She has edited books including Mutant p53 and MDM2 in Cancer and contributed to p53 Protocols. Her work has appeared in journals such as Cell Death & Differentiation and the Journal of Clinical Investigation. Dr. Deb serves in editorial roles and collaborates on cancer biology research programs.
VCU Massey researchers uncover a key weakness in p53 mutations driving lung cancer, paving the way for targeted therapies via checkpoint inhibitors.