Queuosine Mystery Solved: Brain & Cancer Protection | AcademicJobs
Discover how University of Florida and Trinity College researchers solved the 30-year queuosine mystery, revealing its SLC35F2 transporter for brain protection and cancer defense.
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Professor Vincent Kelly is Professor and Academic Co-Ordinator in Biochemistry at Trinity College Dublin. His research focuses on the queuine micronutrient and its role in human physiology, including mechanisms of dietary salvage in mammals and physiological effects in disease. Laboratory investigations have advanced understanding of queuine’s contributions to processes such as autoimmunity, with queuine mimetics shown to reverse clinical symptoms in animal models of multiple sclerosis. Collaborative work has led to the co-founding of the university spin-out company Azadyne to develop queuine-based therapeutics for autoimmune diseases.
Professor Kelly directs the National Transgenics Facility, which provides services including rederivation, IVF, cryopreservation, and CRISPR/Cas9 gene editing to researchers across Ireland. Research interests also encompass RNA modifications in autoimmunity, cancer therapeutics, male infertility, and the development of natural anti-cancer agents. With more than 25 years of experience in transgenic technologies, his group supports projects addressing fertility decline and other physiological challenges through micronutrient studies.
Discover how University of Florida and Trinity College researchers solved the 30-year queuosine mystery, revealing its SLC35F2 transporter for brain protection and cancer defense.