Rate My Professor Wilfried Rossoll

Wilfried O. Rossoll, Ph.D., is an Associate Professor of Neuroscience at Mayo Clinic in Jacksonville, Florida. He serves as Assistant Dean in the Mayo Clinic Graduate School of Biomedical Sciences and as a Consultant in the Department of Neuroscience. Dr. Rossoll leads the Translational Neuroproteomics Laboratory, which investigates the molecular pathomechanisms of abnormal protein aggregation in neurodegenerative diseases including amyotrophic lateral sclerosis, frontotemporal dementia, and Alzheimer’s disease. His research examines how dysfunction, mislocalization, and accumulation of proteins into insoluble aggregates contribute to these conditions, using autopsy brain tissue, in vitro models, and in vivo systems to identify targets for therapies.

Dr. Rossoll earned his Ph.D. and Master of Science degrees from the University of Vienna in Austria. He previously held the position of Associate Director of the Laboratory of Translational Cell Biology Stem Cell Laboratory at Emory University School of Medicine from 2012 to 2017. His professional appointments include Director of the Multi-Omics Mass Spectrometry Core Laboratory at Mayo Clinic since 2024, standing member of the Cellular and Molecular Biology of Neurodegeneration Study Section at the National Institutes of Health since 2024, and Associate Editor of Molecular Neurodegeneration since 2020. His work focuses on developing spatial proteomics methods, profiling neuropathological aggregates, and identifying modifiers of protein aggregation to advance understanding and treatment of proteinopathies.